Depression is one of the most common diseases in the world at all. It belongs to affective disorders.
About 70% of the population suffer during their life from a depressive episode, similar to low back pain. The origin may be different , e.g. death of a relative, divorce, problems with employment such as firing, insolvency etc. Depressive episode may produce dullness, draw back from social surroundings, problems with inappetency and sleep. In severe cases ideas of suicide may occur. Typical for this disease is a feeling of worthlessness. Psychotherapy and medicaments are the treatment of choice and help in the majority of cases to overcome the symptoms of depression. About 10% of these patients cannot be cured by this therapy . When intensive psychotherapy including electro cramp therapy (ECT) do not alleviate the symptoms, VNS can be discussed.